The E23K polymorphism of the KCNJ11gene is associated with lower insulin release in patients with autosomal dominant polycystic kidney disease.
نویسندگان
چکیده
The aim of our study was to investigate an association between E23K KCNJ11 gene polymorphism with anthropometric, biochemical, beta-cell secretion and insulin sensitivity parameters among adult ADPKD patients with normal kidney function and no diagnosis of diabetes. The comparison of genotype-phenotype associations between ADPKD and non-ADPKD subjects could reveal a hypothetical mechanism of genetic determination of diabetes specific for ADPKD patients.
منابع مشابه
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عنوان ژورنال:
- Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia
دوره 33 6 شماره
صفحات -
تاریخ انتشار 2013